HCSGD entry for ASCL2

1. General information

Official gene symbolASCL2
Entrez ID430
Gene full nameachaete-scute complex homolog 2 (Drosophila)
Other gene symbolsASH2 HASH2 MASH2 bHLHa45
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001666Response to hypoxiaIEPbiological_process
GO:0001890Placenta developmentNASbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIDAbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0010626Negative regulation of Schwann cell proliferationIEAbiological_process
GO:0035019Somatic stem cell maintenanceIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0060708Spongiotrophoblast differentiationIEAbiological_process
GO:0060712Spongiotrophoblast layer developmentIEPbiological_process
GO:0070888E-box bindingIDAmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55933888150.82007589760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0641348895
GSE13712_SHEARUp0.0309258813
GSE13712_STATICUp0.0828486411
GSE19018Down-0.0093988290
GSE19899_A1Down-0.0876819394
GSE19899_A2Up0.1217374583
PubMed_21979375_A1Up0.1151290610
PubMed_21979375_A2Down-0.0259357532
GSE35957Down-0.0501511577
GSE36640Down-0.0887795393
GSE54402Up0.3092293646
GSE9593Up0.0302194143
GSE43922Up0.1542126856
GSE24585Up0.0843764407
GSE37065Down-0.0120523643
GSE28863_A1Down-0.1811627432
GSE28863_A2Down-0.0319339812
GSE28863_A3Up0.4134075689
GSE28863_A4Down-0.0139147112
GSE48662Up0.0065063581

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018430MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.