HCSGD entry for ASCL2

1. General information

Official gene symbolASCL2
Entrez ID430
Gene full nameachaete-scute complex homolog 2 (Drosophila)
Other gene symbolsASH2 HASH2 MASH2 bHLHa45
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001666Response to hypoxiaIEPbiological_process
GO:0001890Placenta developmentNASbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIDAbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0010626Negative regulation of Schwann cell proliferationIEAbiological_process
GO:0035019Somatic stem cell maintenanceIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0060708Spongiotrophoblast differentiationIEAbiological_process
GO:0060712Spongiotrophoblast layer developmentIEPbiological_process
GO:0070888E-box bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55933888150.82007589760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0641348895
GSE13712_SHEARUp0.0309258813
GSE13712_STATICUp0.0828486411
GSE19018Down-0.0093988290
GSE19899_A1Down-0.0876819394
GSE19899_A2Up0.1217374583
PubMed_21979375_A1Up0.1151290610
PubMed_21979375_A2Down-0.0259357532
GSE35957Down-0.0501511577
GSE36640Down-0.0887795393
GSE54402Up0.3092293646
GSE9593Up0.0302194143
GSE43922Up0.1542126856
GSE24585Up0.0843764407
GSE37065Down-0.0120523643
GSE28863_A1Down-0.1811627432
GSE28863_A2Down-0.0319339812
GSE28863_A3Up0.4134075689
GSE28863_A4Down-0.0139147112
GSE48662Up0.0065063581

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018430MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.