HCSGD entry for MEIS1
1. General information
| Official gene symbol | MEIS1 |
|---|---|
| Entrez ID | 4211 |
| Gene full name | Meis homeobox 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045638 | Negative regulation of myeloid cell differentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9969082216 | 0.0000624026 | 0.9999902473 | 0.0130889764 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6993788386 |
| GSE13712_SHEAR | Down | -0.5687749530 |
| GSE13712_STATIC | Down | -0.3900275962 |
| GSE19018 | Down | -0.2184699545 |
| GSE19899_A1 | Down | -2.4493758982 |
| GSE19899_A2 | Down | -1.8111389015 |
| PubMed_21979375_A1 | Down | -3.7919485748 |
| PubMed_21979375_A2 | Down | -3.1322639478 |
| GSE35957 | Down | -0.4460986192 |
| GSE36640 | Down | -2.2421744034 |
| GSE54402 | Down | -1.3014472290 |
| GSE9593 | Down | -0.4974144455 |
| GSE43922 | Down | -1.6342019001 |
| GSE24585 | Down | -0.5392860886 |
| GSE37065 | Up | 0.5341490021 |
| GSE28863_A1 | Up | 0.1476760335 |
| GSE28863_A2 | Down | -0.1782665695 |
| GSE28863_A3 | Down | -0.4918783094 |
| GSE28863_A4 | Down | -0.4575424012 |
| GSE48662 | Down | -0.0986141040 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT000189 | Luciferase reporter assay//Microarray//Western blot//Reporter assay;Western blot;Other | Functional MTI | 18308931 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT000287 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 18950466 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT000287 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT004946 | qRT-PCR | Functional MTI (Weak) | 17942906 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT004962 | qRT-PCR | Functional MTI (Weak) | 17942906 |
| hsa-miR-495-3p | MIMAT0002817 | MIRT007195 | Immunoblot//Immunohistochemistry//Luciferase reporter assay//Microarray//qRT-PCR//Western blot | Functional MTI | 23132946 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027307 | Western blot | Functional MTI | 18308931 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030714 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-484 | MIMAT0002174 | MIRT041845 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | 1 | hsa-miR-155 | {Western blot} | {overexpression} | 18950466 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
