HCSGD entry for MEIS1


1. General information

Official gene symbolMEIS1
Entrez ID4211
Gene full nameMeis homeobox 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045638Negative regulation of myeloid cell differentiationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99690822160.00006240260.99999024730.0130889764

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6993788386
GSE13712_SHEARDown-0.5687749530
GSE13712_STATICDown-0.3900275962
GSE19018Down-0.2184699545
GSE19899_A1Down-2.4493758982
GSE19899_A2Down-1.8111389015
PubMed_21979375_A1Down-3.7919485748
PubMed_21979375_A2Down-3.1322639478
GSE35957Down-0.4460986192
GSE36640Down-2.2421744034
GSE54402Down-1.3014472290
GSE9593Down-0.4974144455
GSE43922Down-1.6342019001
GSE24585Down-0.5392860886
GSE37065Up0.5341490021
GSE28863_A1Up0.1476760335
GSE28863_A2Down-0.1782665695
GSE28863_A3Down-0.4918783094
GSE28863_A4Down-0.4575424012
GSE48662Down-0.0986141040

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-204-5pMIMAT0000265MIRT000189Luciferase reporter assay//Microarray//Western blot//Reporter assay;Western blot;OtherFunctional MTI18308931
hsa-miR-155-5pMIMAT0000646MIRT000287Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI18950466
hsa-miR-155-5pMIMAT0000646MIRT000287ProteomicsFunctional MTI (Weak)18668040
hsa-miR-98-5pMIMAT0000096MIRT004946qRT-PCRFunctional MTI (Weak)17942906
hsa-let-7a-5pMIMAT0000062MIRT004962qRT-PCRFunctional MTI (Weak)17942906
hsa-miR-495-3pMIMAT0002817MIRT007195Immunoblot//Immunohistochemistry//Luciferase reporter assay//Microarray//qRT-PCR//Western blotFunctional MTI23132946
hsa-miR-101-3pMIMAT0000099MIRT027307Western blotFunctional MTI18308931
hsa-miR-21-5pMIMAT0000076MIRT030714MicroarrayFunctional MTI (Weak)18591254
hsa-miR-484MIMAT0002174MIRT041845CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-155-5pMIMAT00006461hsa-miR-155{Western blot}{overexpression}18950466
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.