HCSGD entry for MEFV
1. General information
| Official gene symbol | MEFV |
|---|---|
| Entrez ID | 4210 |
| Gene full name | Mediterranean fever |
| Other gene symbols | FMF MEF TRIM20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IDA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005875 | Microtubule associated complex | IDA | cellular_component |
| GO:0006954 | Inflammatory response | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IEA NAS | molecular_function |
| GO:0032691 | Negative regulation of interleukin-1 beta production | IMP | biological_process |
| GO:0032695 | Negative regulation of interleukin-12 production | IMP | biological_process |
| GO:0035872 | Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050728 | Negative regulation of inflammatory response | IMP | biological_process |
| GO:0071641 | Negative regulation of macrophage inflammatory protein 1 alpha production | IMP | biological_process |
| GO:2001056 | Positive regulation of cysteine-type endopeptidase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2909242354 | 0.5328374340 | 0.9898496705 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0782668368 |
| GSE13712_SHEAR | Down | -0.0504714800 |
| GSE13712_STATIC | Down | -0.0473457016 |
| GSE19018 | Up | 0.0335274182 |
| GSE19899_A1 | Up | 0.1182920840 |
| GSE19899_A2 | Up | 0.1525927838 |
| PubMed_21979375_A1 | Down | -0.3254890695 |
| PubMed_21979375_A2 | Down | -0.4314323899 |
| GSE35957 | Up | 0.0896118832 |
| GSE36640 | Down | -0.0516283051 |
| GSE54402 | Down | -0.0114880910 |
| GSE9593 | Down | -0.0682595479 |
| GSE43922 | Up | 0.0860335494 |
| GSE24585 | Down | -0.1850748883 |
| GSE37065 | Up | 0.3748470002 |
| GSE28863_A1 | Down | -0.1414710350 |
| GSE28863_A2 | Down | -0.0034859033 |
| GSE28863_A3 | Up | 0.3518713867 |
| GSE28863_A4 | Down | -0.0016866208 |
| GSE48662 | Up | 1.5437962208 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
