HCSGD entry for LRPAP1

1. General information

Official gene symbolLRPAP1
Entrez ID4043
Gene full namelow density lipoprotein receptor-related protein associated protein 1
Other gene symbolsA2MRAP A2RAP HBP44 MRAP RAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004873Asialoglycoprotein receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006457Protein foldingTASbiological_process
GO:0006898Receptor-mediated endocytosisTASbiological_process
GO:0008201Heparin bindingIEAmolecular_function
GO:0009986Cell surfaceIEAcellular_component
GO:0010469Regulation of receptor activityIDAbiological_process
GO:0010916Negative regulation of very-low-density lipoprotein particle clearanceIDAbiological_process
GO:0016021Integral component of membraneTAScellular_component
GO:0016192Vesicle-mediated transportTASbiological_process
GO:0031982VesicleIEAcellular_component
GO:0032091Negative regulation of protein bindingIDAbiological_process
GO:0035473Lipase bindingIEAmolecular_function
GO:0048019Receptor antagonist activityIDAmolecular_function
GO:0048237Rough endoplasmic reticulum lumenIEAcellular_component
GO:0050750Low-density lipoprotein particle receptor bindingIDAmolecular_function
GO:0051082Unfolded protein bindingTASmolecular_function
GO:0070326Very-low-density lipoprotein particle receptor bindingIPImolecular_function
GO:1900116Extracellular negative regulation of signal transductionIDAbiological_process
GO:1900222Negative regulation of beta-amyloid clearanceIGIbiological_process
GO:2000272Negative regulation of receptor activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03842737740.78474333420.44342262171.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5167451599
GSE13712_SHEARDown-0.6459555368
GSE13712_STATICDown-0.5515506572
GSE19018Up0.3172844663
GSE19899_A1Down-0.0851118281
GSE19899_A2Up0.4687496013
PubMed_21979375_A1Up0.1360409296
PubMed_21979375_A2Up0.3234582268
GSE35957Up0.4474178753
GSE36640Up1.1912024283
GSE54402Down-0.1454784715
GSE9593Up0.3176624805
GSE43922Up0.1061055253
GSE24585Up0.0697159683
GSE37065Up0.3251593180
GSE28863_A1Down-0.1060545072
GSE28863_A2Up0.0775964249
GSE28863_A3Up0.0649778118
GSE28863_A4Down-0.0889901992
GSE48662Up0.9138059480

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029205MicroarrayFunctional MTI (Weak)19088304
hsa-miR-615-3pMIMAT0003283MIRT040189CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.