HCSGD entry for LRPAP1

1. General information

Official gene symbolLRPAP1
Entrez ID4043
Gene full namelow density lipoprotein receptor-related protein associated protein 1
Other gene symbolsA2MRAP A2RAP HBP44 MRAP RAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004873Asialoglycoprotein receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006457Protein foldingTASbiological_process
GO:0006898Receptor-mediated endocytosisTASbiological_process
GO:0008201Heparin bindingIEAmolecular_function
GO:0009986Cell surfaceIEAcellular_component
GO:0010469Regulation of receptor activityIDAbiological_process
GO:0010916Negative regulation of very-low-density lipoprotein particle clearanceIDAbiological_process
GO:0016021Integral component of membraneTAScellular_component
GO:0016192Vesicle-mediated transportTASbiological_process
GO:0031982VesicleIEAcellular_component
GO:0032091Negative regulation of protein bindingIDAbiological_process
GO:0035473Lipase bindingIEAmolecular_function
GO:0048019Receptor antagonist activityIDAmolecular_function
GO:0048237Rough endoplasmic reticulum lumenIEAcellular_component
GO:0050750Low-density lipoprotein particle receptor bindingIDAmolecular_function
GO:0051082Unfolded protein bindingTASmolecular_function
GO:0070326Very-low-density lipoprotein particle receptor bindingIPImolecular_function
GO:1900116Extracellular negative regulation of signal transductionIDAbiological_process
GO:1900222Negative regulation of beta-amyloid clearanceIGIbiological_process
GO:2000272Negative regulation of receptor activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03842737740.78474333420.44342262171.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5167451599
GSE13712_SHEARDown-0.6459555368
GSE13712_STATICDown-0.5515506572
GSE19018Up0.3172844663
GSE19899_A1Down-0.0851118281
GSE19899_A2Up0.4687496013
PubMed_21979375_A1Up0.1360409296
PubMed_21979375_A2Up0.3234582268
GSE35957Up0.4474178753
GSE36640Up1.1912024283
GSE54402Down-0.1454784715
GSE9593Up0.3176624805
GSE43922Up0.1061055253
GSE24585Up0.0697159683
GSE37065Up0.3251593180
GSE28863_A1Down-0.1060545072
GSE28863_A2Up0.0775964249
GSE28863_A3Up0.0649778118
GSE28863_A4Down-0.0889901992
GSE48662Up0.9138059480

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029205MicroarrayFunctional MTI (Weak)19088304
hsa-miR-615-3pMIMAT0003283MIRT040189CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.