HCSGD entry for LMX1A
1. General information
| Official gene symbol | LMX1A |
|---|---|
| Entrez ID | 4009 |
| Gene full name | LIM homeobox transcription factor 1, alpha |
| Other gene symbols | LMX1 LMX1.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001558 | Regulation of cell growth | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007411 | Axon guidance | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0021542 | Dentate gyrus development | IEA | biological_process |
| GO:0021549 | Cerebellum development | IEA | biological_process |
| GO:0021953 | Central nervous system neuron differentiation | IEA | biological_process |
| GO:0030901 | Midbrain development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0071542 | Dopaminergic neuron differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7528582995 | 0.7216283082 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0817377526 |
| GSE13712_SHEAR | Down | -0.0574768618 |
| GSE13712_STATIC | Down | -0.0093456200 |
| GSE19018 | Down | -0.1348873131 |
| GSE19899_A1 | Up | 0.0119545478 |
| GSE19899_A2 | Up | 0.0874535650 |
| PubMed_21979375_A1 | Up | 0.0062806627 |
| PubMed_21979375_A2 | Up | 0.0064216065 |
| GSE35957 | Up | 0.0254723406 |
| GSE36640 | Down | -0.0495565081 |
| GSE54402 | Up | 0.0539706177 |
| GSE9593 | Down | -0.1101678455 |
| GSE43922 | Up | 0.0613339247 |
| GSE24585 | Up | 0.1595295976 |
| GSE37065 | Down | -0.0828883406 |
| GSE28863_A1 | Down | -0.1712602252 |
| GSE28863_A2 | Up | 0.1422372243 |
| GSE28863_A3 | Up | 0.2759294312 |
| GSE28863_A4 | Up | 0.1263741447 |
| GSE48662 | Down | -0.1387651941 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
