HCSGD entry for LMX1A


1. General information

Official gene symbolLMX1A
Entrez ID4009
Gene full nameLIM homeobox transcription factor 1, alpha
Other gene symbolsLMX1 LMX1.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0021542Dentate gyrus developmentIEAbiological_process
GO:0021549Cerebellum developmentIEAbiological_process
GO:0021953Central nervous system neuron differentiationIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045665Negative regulation of neuron differentiationIEAbiological_process
GO:0071542Dopaminergic neuron differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75285829950.72162830820.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0817377526
GSE13712_SHEARDown-0.0574768618
GSE13712_STATICDown-0.0093456200
GSE19018Down-0.1348873131
GSE19899_A1Up0.0119545478
GSE19899_A2Up0.0874535650
PubMed_21979375_A1Up0.0062806627
PubMed_21979375_A2Up0.0064216065
GSE35957Up0.0254723406
GSE36640Down-0.0495565081
GSE54402Up0.0539706177
GSE9593Down-0.1101678455
GSE43922Up0.0613339247
GSE24585Up0.1595295976
GSE37065Down-0.0828883406
GSE28863_A1Down-0.1712602252
GSE28863_A2Up0.1422372243
GSE28863_A3Up0.2759294312
GSE28863_A4Up0.1263741447
GSE48662Down-0.1387651941

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.