HCSGD entry for ASIC2

1. General information

Official gene symbolASIC2
Entrez ID40
Gene full nameacid-sensing (proton-gated) ion channel 2
Other gene symbolsACCN ACCN1 ASIC2a BNC1 BNaC1 MDEG hBNaC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001101Response to acidIEAbiological_process
GO:0003026Regulation of systemic arterial blood pressure by aortic arch baroreceptor feedbackIEAbiological_process
GO:0005248Voltage-gated sodium channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0007422Peripheral nervous system developmentTASbiological_process
GO:0007602PhototransductionIEAbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0015280Ligand-gated sodium channel activityIEAmolecular_function
GO:0015672Monovalent inorganic cation transportTASbiological_process
GO:0019229Regulation of vasoconstrictionIEAbiological_process
GO:0022839Ion gated channel activityIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035418Protein localization to synapseIEAbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043197Dendritic spineIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0050974Detection of mechanical stimulus involved in sensory perceptionIEAbiological_process
GO:0051965Positive regulation of synapse assemblyIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94592620720.35327459440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1414999603
GSE13712_SHEARDown-0.0134609183
GSE13712_STATICDown-0.2657382245
GSE19018Down-0.1182426699
GSE19899_A1Down-0.0376480263
GSE19899_A2Down-0.4235139955
PubMed_21979375_A1Up0.1415496521
PubMed_21979375_A2Down-0.0558793458
GSE35957Up0.0293170552
GSE36640Down-0.2113361271
GSE54402Down-0.1428533111
GSE9593Up0.0428612186
GSE43922Up0.0126622421
GSE24585Up0.0577988481
GSE37065Down-0.0690512089
GSE28863_A1Down-0.0535913558
GSE28863_A2Down-0.0201957126
GSE28863_A3Up0.0964587871
GSE28863_A4Up0.0926146677
GSE48662Up0.0988799466

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AmilorideDB00594 APRD00790 | EXPT00514

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.