HCSGD entry for ASIC2

1. General information

Official gene symbolASIC2
Entrez ID40
Gene full nameacid-sensing (proton-gated) ion channel 2
Other gene symbolsACCN ACCN1 ASIC2a BNC1 BNaC1 MDEG hBNaC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001101Response to acidIEAbiological_process
GO:0003026Regulation of systemic arterial blood pressure by aortic arch baroreceptor feedbackIEAbiological_process
GO:0005248Voltage-gated sodium channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0007422Peripheral nervous system developmentTASbiological_process
GO:0007602PhototransductionIEAbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0015280Ligand-gated sodium channel activityIEAmolecular_function
GO:0015672Monovalent inorganic cation transportTASbiological_process
GO:0019229Regulation of vasoconstrictionIEAbiological_process
GO:0022839Ion gated channel activityIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035418Protein localization to synapseIEAbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043197Dendritic spineIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0050974Detection of mechanical stimulus involved in sensory perceptionIEAbiological_process
GO:0051965Positive regulation of synapse assemblyIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94592620720.35327459440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1414999603
GSE13712_SHEARDown-0.0134609183
GSE13712_STATICDown-0.2657382245
GSE19018Down-0.1182426699
GSE19899_A1Down-0.0376480263
GSE19899_A2Down-0.4235139955
PubMed_21979375_A1Up0.1415496521
PubMed_21979375_A2Down-0.0558793458
GSE35957Up0.0293170552
GSE36640Down-0.2113361271
GSE54402Down-0.1428533111
GSE9593Up0.0428612186
GSE43922Up0.0126622421
GSE24585Up0.0577988481
GSE37065Down-0.0690512089
GSE28863_A1Down-0.0535913558
GSE28863_A2Down-0.0201957126
GSE28863_A3Up0.0964587871
GSE28863_A4Up0.0926146677
GSE48662Up0.0988799466

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AmilorideDB00594 APRD00790 | EXPT00514

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.