HCSGD entry for HES3

1. General information

Official gene symbolHES3
Entrez ID390992
Gene full namehairy and enhancer of split 3 (Drosophila)
Other gene symbolsbHLHb43
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008134Transcription factor bindingNASmolecular_function
GO:0021555Midbrain-hindbrain boundary morphogenesisIEAbiological_process
GO:0021557Oculomotor nerve developmentIEAbiological_process
GO:0021558Trochlear nerve developmentIEAbiological_process
GO:0021575Hindbrain morphogenesisIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0060164Regulation of timing of neuron differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64295443940.95075897950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.0883018521
GSE24585Up0.1024090483
GSE37065Down-0.1115785748
GSE28863_A1Down-0.0733099550
GSE28863_A2Up0.0802265555
GSE28863_A3Up0.2171499129
GSE28863_A4Up0.1035694169
GSE48662Up0.0493004496

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.