HCSGD entry for HES3

1. General information

Official gene symbolHES3
Entrez ID390992
Gene full namehairy and enhancer of split 3 (Drosophila)
Other gene symbolsbHLHb43
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008134Transcription factor bindingNASmolecular_function
GO:0021555Midbrain-hindbrain boundary morphogenesisIEAbiological_process
GO:0021557Oculomotor nerve developmentIEAbiological_process
GO:0021558Trochlear nerve developmentIEAbiological_process
GO:0021575Hindbrain morphogenesisIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0060164Regulation of timing of neuron differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64295443940.95075897950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.0883018521
GSE24585Up0.1024090483
GSE37065Down-0.1115785748
GSE28863_A1Down-0.0733099550
GSE28863_A2Up0.0802265555
GSE28863_A3Up0.2171499129
GSE28863_A4Up0.1035694169
GSE48662Up0.0493004496

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.