HCSGD entry for KRT16
1. General information
| Official gene symbol | KRT16 |
|---|---|
| Entrez ID | 3868 |
| Gene full name | keratin 16 |
| Other gene symbols | CK16 FNEPPK K16 K1CP KRT16A NEPPK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005200 | Structural constituent of cytoskeleton | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005882 | Intermediate filament | IEA NAS | cellular_component |
| GO:0007010 | Cytoskeleton organization | NAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0010043 | Response to zinc ion | IEA | biological_process |
| GO:0010212 | Response to ionizing radiation | IEA | biological_process |
| GO:0030855 | Epithelial cell differentiation | IEA | biological_process |
| GO:0045095 | Keratin filament | IEA | cellular_component |
| GO:0045104 | Intermediate filament cytoskeleton organization | IEA | biological_process |
| GO:0071944 | Cell periphery | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0913467118 | 0.9463926485 | 0.6364046585 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0784445377 |
| GSE13712_SHEAR | Down | -0.1616780365 |
| GSE13712_STATIC | Down | -0.0181776006 |
| GSE19018 | Up | 0.1369243989 |
| GSE19899_A1 | Up | 0.2124137971 |
| GSE19899_A2 | Down | -0.1321391818 |
| PubMed_21979375_A1 | Up | 0.1732306321 |
| PubMed_21979375_A2 | Up | 0.2305140368 |
| GSE35957 | Up | 0.3618049187 |
| GSE36640 | Up | 0.0620127406 |
| GSE54402 | Down | -0.0543672250 |
| GSE9593 | Up | 0.0343622638 |
| GSE43922 | Up | 0.1236548083 |
| GSE24585 | Up | 0.2940426776 |
| GSE37065 | Up | 0.1513222018 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 1.0013098895 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25635860 | The acetylation of Histone H3 (K9) and H4 (K16) of the IL-8 and IL-6 promoter regions gradually increased during cellular senescence |
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