HCSGD entry for KRT16


1. General information

Official gene symbolKRT16
Entrez ID3868
Gene full namekeratin 16
Other gene symbolsCK16 FNEPPK K16 K1CP KRT16A NEPPK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005200Structural constituent of cytoskeletonIEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005882Intermediate filamentIEA NAScellular_component
GO:0007010Cytoskeleton organizationNASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008544Epidermis developmentTASbiological_process
GO:0010043Response to zinc ionIEAbiological_process
GO:0010212Response to ionizing radiationIEAbiological_process
GO:0030855Epithelial cell differentiationIEAbiological_process
GO:0045095Keratin filamentIEAcellular_component
GO:0045104Intermediate filament cytoskeleton organizationIEAbiological_process
GO:0071944Cell peripheryIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09134671180.94639264850.63640465851.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0784445377
GSE13712_SHEARDown-0.1616780365
GSE13712_STATICDown-0.0181776006
GSE19018Up0.1369243989
GSE19899_A1Up0.2124137971
GSE19899_A2Down-0.1321391818
PubMed_21979375_A1Up0.1732306321
PubMed_21979375_A2Up0.2305140368
GSE35957Up0.3618049187
GSE36640Up0.0620127406
GSE54402Down-0.0543672250
GSE9593Up0.0343622638
GSE43922Up0.1236548083
GSE24585Up0.2940426776
GSE37065Up0.1513222018
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up1.0013098895

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25635860The acetylation of Histone H3 (K9) and H4 (K16) of the IL-8 and IL-6 promoter regions gradually increased during cellular senescence
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