HCSGD entry for KCNK1
1. General information
| Official gene symbol | KCNK1 |
|---|---|
| Entrez ID | 3775 |
| Gene full name | potassium channel, subfamily K, member 1 |
| Other gene symbols | DPK HOHO K2P1 K2p1.1 KCNO1 TWIK-1 TWIK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005242 | Inward rectifier potassium channel activity | TAS | molecular_function |
| GO:0005267 | Potassium channel activity | IEA | molecular_function |
| GO:0005768 | Endosome | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006813 | Potassium ion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0031526 | Brush border membrane | IEA | cellular_component |
| GO:0035094 | Response to nicotine | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5618797348 | 0.3080318111 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4708598620 |
| GSE13712_SHEAR | Down | -0.6164145903 |
| GSE13712_STATIC | Down | -0.4032306813 |
| GSE19018 | Up | 0.3568163698 |
| GSE19899_A1 | Down | -0.0916213150 |
| GSE19899_A2 | Down | -0.0263562690 |
| PubMed_21979375_A1 | Up | 0.1132459890 |
| PubMed_21979375_A2 | Down | -0.1795545659 |
| GSE35957 | Down | -0.3132463046 |
| GSE36640 | Down | -0.3011941611 |
| GSE54402 | Up | 0.1202037327 |
| GSE9593 | Up | 0.0113248118 |
| GSE43922 | Up | 0.0274822011 |
| GSE24585 | Down | -0.1869338912 |
| GSE37065 | Up | 0.4253015290 |
| GSE28863_A1 | Down | -0.1171832802 |
| GSE28863_A2 | Up | 0.3170184354 |
| GSE28863_A3 | Up | 0.0502891428 |
| GSE28863_A4 | Down | -0.1332271121 |
| GSE48662 | Up | 0.1175583555 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019653 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022480 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028202 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
