HCSGD entry for KCNK1


1. General information

Official gene symbolKCNK1
Entrez ID3775
Gene full namepotassium channel, subfamily K, member 1
Other gene symbolsDPK HOHO K2P1 K2p1.1 KCNO1 TWIK-1 TWIK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005242Inward rectifier potassium channel activityTASmolecular_function
GO:0005267Potassium channel activityIEAmolecular_function
GO:0005768EndosomeIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0031526Brush border membraneIEAcellular_component
GO:0035094Response to nicotineIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56187973480.30803181110.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4708598620
GSE13712_SHEARDown-0.6164145903
GSE13712_STATICDown-0.4032306813
GSE19018Up0.3568163698
GSE19899_A1Down-0.0916213150
GSE19899_A2Down-0.0263562690
PubMed_21979375_A1Up0.1132459890
PubMed_21979375_A2Down-0.1795545659
GSE35957Down-0.3132463046
GSE36640Down-0.3011941611
GSE54402Up0.1202037327
GSE9593Up0.0113248118
GSE43922Up0.0274822011
GSE24585Down-0.1869338912
GSE37065Up0.4253015290
GSE28863_A1Down-0.1171832802
GSE28863_A2Up0.3170184354
GSE28863_A3Up0.0502891428
GSE28863_A4Down-0.1332271121
GSE48662Up0.1175583555

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IbutilideDB00308 APRD01025
Quinidine barbiturateDB01346 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019653SequencingFunctional MTI (Weak)20371350
hsa-miR-124-3pMIMAT0000422MIRT022480MicroarrayFunctional MTI (Weak)18668037
hsa-miR-33a-5pMIMAT0000091MIRT028202SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.