HCSGD entry for KCNJ12

1. General information

Official gene symbolKCNJ12
Entrez ID3768
Gene full namepotassium inwardly-rectifying channel, subfamily J, member 12
Other gene symbolsIRK-2 IRK2 KCNJN1 Kir2.2 Kir2.2v hIRK hIRK1 hkir2.2x kcnj12x
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005242Inward rectifier potassium channel activityIDAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportIDAbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008016Regulation of heart contractionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0031224Intrinsic component of membraneIDAcellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0051289Protein homotetramerizationIDAbiological_process
GO:0055085Transmembrane transportIDAbiological_process
GO:0071805Potassium ion transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09254867220.99165483070.63896198951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0379891795
GSE28863_A2Up0.4427278696
GSE28863_A3Up0.4649926058
GSE28863_A4Down-0.0290294887
GSE48662Up0.2011212197

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DofetilideDB00204 APRD00367

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.