HCSGD entry for KCNJ12

1. General information

Official gene symbolKCNJ12
Entrez ID3768
Gene full namepotassium inwardly-rectifying channel, subfamily J, member 12
Other gene symbolsIRK-2 IRK2 KCNJN1 Kir2.2 Kir2.2v hIRK hIRK1 hkir2.2x kcnj12x
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005242Inward rectifier potassium channel activityIDAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportIDAbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008016Regulation of heart contractionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0031224Intrinsic component of membraneIDAcellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0051289Protein homotetramerizationIDAbiological_process
GO:0055085Transmembrane transportIDAbiological_process
GO:0071805Potassium ion transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09254867220.99165483070.63896198951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0379891795
GSE28863_A2Up0.4427278696
GSE28863_A3Up0.4649926058
GSE28863_A4Down-0.0290294887
GSE48662Up0.2011212197

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DofetilideDB00204 APRD00367

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.