HCSGD entry for KCND1
1. General information
| Official gene symbol | KCND1 |
|---|---|
| Entrez ID | 3750 |
| Gene full name | potassium voltage-gated channel, Shal-related subfamily, member 1 |
| Other gene symbols | KV4.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005249 | Voltage-gated potassium channel activity | IEA | molecular_function |
| GO:0005251 | Delayed rectifier potassium channel activity | IBA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IEA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9325383838 | 0.0662466130 | 0.9999902473 | 0.4853661102 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1892836963 |
| GSE13712_SHEAR | Down | -0.2621239038 |
| GSE13712_STATIC | Down | -0.4686886084 |
| GSE19018 | Up | 0.1009836973 |
| GSE19899_A1 | Up | 0.0156329378 |
| GSE19899_A2 | Down | -0.2714527146 |
| PubMed_21979375_A1 | Down | -0.3780561499 |
| PubMed_21979375_A2 | Down | -0.2485759629 |
| GSE35957 | Down | -0.2465443232 |
| GSE36640 | Up | 0.4371949670 |
| GSE54402 | Down | -0.0910178279 |
| GSE9593 | Down | -0.2286245540 |
| GSE43922 | Down | -0.6573330226 |
| GSE24585 | Down | -0.2684623287 |
| GSE37065 | Down | -0.4793998712 |
| GSE28863_A1 | Up | 0.2090578953 |
| GSE28863_A2 | Up | 0.2845050198 |
| GSE28863_A3 | Down | -0.0473638702 |
| GSE28863_A4 | Up | 0.1837332600 |
| GSE48662 | Down | -0.0590436672 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Dalfampridine | DB06637 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023663 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029175 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
