HCSGD entry for KCND1


1. General information

Official gene symbolKCND1
Entrez ID3750
Gene full namepotassium voltage-gated channel, Shal-related subfamily, member 1
Other gene symbolsKV4.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityIEAmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93253838380.06624661300.99999024730.4853661102

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1892836963
GSE13712_SHEARDown-0.2621239038
GSE13712_STATICDown-0.4686886084
GSE19018Up0.1009836973
GSE19899_A1Up0.0156329378
GSE19899_A2Down-0.2714527146
PubMed_21979375_A1Down-0.3780561499
PubMed_21979375_A2Down-0.2485759629
GSE35957Down-0.2465443232
GSE36640Up0.4371949670
GSE54402Down-0.0910178279
GSE9593Down-0.2286245540
GSE43922Down-0.6573330226
GSE24585Down-0.2684623287
GSE37065Down-0.4793998712
GSE28863_A1Up0.2090578953
GSE28863_A2Up0.2845050198
GSE28863_A3Down-0.0473638702
GSE28863_A4Up0.1837332600
GSE48662Down-0.0590436672

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023663MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029175MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.