HCSGD entry for KCNA3

1. General information

Official gene symbolKCNA3
Entrez ID3738
Gene full namepotassium voltage-gated channel, shaker-related subfamily, member 3
Other gene symbolsHGK5 HLK3 HPCN3 HUKIII KV1.3 MK3 PCN3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005244Voltage-gated ion channel activityTASmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0015271Outward rectifier potassium channel activityIEAmolecular_function
GO:0045121Membrane raftIEAcellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68553886250.38648126210.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0222699919
GSE13712_SHEARDown-0.0257406660
GSE13712_STATICUp0.0404289395
GSE19018Down-0.1202666893
GSE19899_A1Up0.2976946381
GSE19899_A2Up0.0436627497
PubMed_21979375_A1Down-0.2305052742
PubMed_21979375_A2Down-0.0464462402
GSE35957Up0.2633912722
GSE36640Down-0.2162013754
GSE54402Down-0.2413873574
GSE9593Up0.0012604395
GSE43922Up0.0146001632
GSE24585Down-0.5776436060
GSE37065Down-0.0272544429
GSE28863_A1Down-0.2996916518
GSE28863_A2Up0.7462856942
GSE28863_A3Up0.1889550184
GSE28863_A4Down-0.0137425500
GSE48662Up0.0353562973

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.