HCSGD entry for KCNA3


1. General information

Official gene symbolKCNA3
Entrez ID3738
Gene full namepotassium voltage-gated channel, shaker-related subfamily, member 3
Other gene symbolsHGK5 HLK3 HPCN3 HUKIII KV1.3 MK3 PCN3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005244Voltage-gated ion channel activityTASmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0015271Outward rectifier potassium channel activityIEAmolecular_function
GO:0045121Membrane raftIEAcellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68553886250.38648126210.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0222699919
GSE13712_SHEARDown-0.0257406660
GSE13712_STATICUp0.0404289395
GSE19018Down-0.1202666893
GSE19899_A1Up0.2976946381
GSE19899_A2Up0.0436627497
PubMed_21979375_A1Down-0.2305052742
PubMed_21979375_A2Down-0.0464462402
GSE35957Up0.2633912722
GSE36640Down-0.2162013754
GSE54402Down-0.2413873574
GSE9593Up0.0012604395
GSE43922Up0.0146001632
GSE24585Down-0.5776436060
GSE37065Down-0.0272544429
GSE28863_A1Down-0.2996916518
GSE28863_A2Up0.7462856942
GSE28863_A3Up0.1889550184
GSE28863_A4Down-0.0137425500
GSE48662Up0.0353562973

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.