HCSGD entry for ITPK1

1. General information

Official gene symbolITPK1
Entrez ID3705
Gene full nameinositol-tetrakisphosphate 1-kinase
Other gene symbolsITRPK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0003824Catalytic activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016311DephosphorylationTASbiological_process
GO:0016853Isomerase activityIEAmolecular_function
GO:0032957Inositol trisphosphate metabolic processIEAbiological_process
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0047325Inositol tetrakisphosphate 1-kinase activityIEA TASmolecular_function
GO:0052725Inositol-1,3,4-trisphosphate 6-kinase activityIEA TASmolecular_function
GO:0052726Inositol-1,3,4-trisphosphate 5-kinase activityIEA TASmolecular_function
GO:0052825Inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activityTASmolecular_function
GO:0052830Inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activityTASmolecular_function
GO:0052831Inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activityTASmolecular_function
GO:0052835Inositol-3,4,6-trisphosphate 1-kinase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73024993350.64531856310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0942558584
GSE13712_SHEARDown-0.3354813182
GSE13712_STATICDown-0.1354085833
GSE19018Up0.0504811116
GSE19899_A1Up0.0063144350
GSE19899_A2Up0.0828220975
PubMed_21979375_A1Up0.1408123130
PubMed_21979375_A2Up0.1585335742
GSE35957Up0.2863497034
GSE36640Down-0.3939291604
GSE54402Up0.1424197568
GSE9593Down-0.2892246695
GSE43922Up0.0350915704
GSE24585Down-0.1215362616
GSE37065Down-0.1673749344
GSE28863_A1Up0.0006891132
GSE28863_A2Down-0.0927136540
GSE28863_A3Up0.0347310292
GSE28863_A4Up0.0342459958
GSE48662Up0.3227003009

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT039431CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.