HCSGD entry for ITPK1

1. General information

Official gene symbolITPK1
Entrez ID3705
Gene full nameinositol-tetrakisphosphate 1-kinase
Other gene symbolsITRPK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0003824Catalytic activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016311DephosphorylationTASbiological_process
GO:0016853Isomerase activityIEAmolecular_function
GO:0032957Inositol trisphosphate metabolic processIEAbiological_process
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0047325Inositol tetrakisphosphate 1-kinase activityIEA TASmolecular_function
GO:0052725Inositol-1,3,4-trisphosphate 6-kinase activityIEA TASmolecular_function
GO:0052726Inositol-1,3,4-trisphosphate 5-kinase activityIEA TASmolecular_function
GO:0052825Inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activityTASmolecular_function
GO:0052830Inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activityTASmolecular_function
GO:0052831Inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activityTASmolecular_function
GO:0052835Inositol-3,4,6-trisphosphate 1-kinase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73024993350.64531856310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0942558584
GSE13712_SHEARDown-0.3354813182
GSE13712_STATICDown-0.1354085833
GSE19018Up0.0504811116
GSE19899_A1Up0.0063144350
GSE19899_A2Up0.0828220975
PubMed_21979375_A1Up0.1408123130
PubMed_21979375_A2Up0.1585335742
GSE35957Up0.2863497034
GSE36640Down-0.3939291604
GSE54402Up0.1424197568
GSE9593Down-0.2892246695
GSE43922Up0.0350915704
GSE24585Down-0.1215362616
GSE37065Down-0.1673749344
GSE28863_A1Up0.0006891132
GSE28863_A2Down-0.0927136540
GSE28863_A3Up0.0347310292
GSE28863_A4Up0.0342459958
GSE48662Up0.3227003009

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT039431CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.