HCSGD entry for ITIH3
1. General information
| Official gene symbol | ITIH3 |
|---|---|
| Entrez ID | 3699 |
| Gene full name | inter-alpha-trypsin inhibitor heavy chain 3 |
| Other gene symbols | H3P |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004866 | Endopeptidase inhibitor activity | TAS | molecular_function |
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | NAS | cellular_component |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0030212 | Hyaluronan metabolic process | IEA | biological_process |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7492619163 | 0.2536995137 | 0.9999902473 | 0.9663454282 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2075646879 |
| GSE13712_SHEAR | Down | -0.2033561115 |
| GSE13712_STATIC | Up | 0.2912390806 |
| GSE19018 | Down | -0.0344017812 |
| GSE19899_A1 | Down | -0.0164424984 |
| GSE19899_A2 | Down | -0.0031389896 |
| PubMed_21979375_A1 | Down | -0.5682774213 |
| PubMed_21979375_A2 | Down | -0.5163849542 |
| GSE35957 | Up | 0.1454441807 |
| GSE36640 | Down | -0.0279106976 |
| GSE54402 | Up | 0.2147986160 |
| GSE9593 | Down | -0.0975558853 |
| GSE43922 | Up | 0.0114439738 |
| GSE24585 | Up | 0.0044301509 |
| GSE37065 | Down | -0.0607011342 |
| GSE28863_A1 | Down | -0.3514974220 |
| GSE28863_A2 | Down | -0.2222607713 |
| GSE28863_A3 | Up | 0.2138869013 |
| GSE28863_A4 | Up | 0.1691905360 |
| GSE48662 | Up | 0.5194793210 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
