HCSGD entry for ITIH3


1. General information

Official gene symbolITIH3
Entrez ID3699
Gene full nameinter-alpha-trypsin inhibitor heavy chain 3
Other gene symbolsH3P
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004866Endopeptidase inhibitor activityTASmolecular_function
GO:0004867Serine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0030212Hyaluronan metabolic processIEAbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74926191630.25369951370.99999024730.9663454282

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2075646879
GSE13712_SHEARDown-0.2033561115
GSE13712_STATICUp0.2912390806
GSE19018Down-0.0344017812
GSE19899_A1Down-0.0164424984
GSE19899_A2Down-0.0031389896
PubMed_21979375_A1Down-0.5682774213
PubMed_21979375_A2Down-0.5163849542
GSE35957Up0.1454441807
GSE36640Down-0.0279106976
GSE54402Up0.2147986160
GSE9593Down-0.0975558853
GSE43922Up0.0114439738
GSE24585Up0.0044301509
GSE37065Down-0.0607011342
GSE28863_A1Down-0.3514974220
GSE28863_A2Down-0.2222607713
GSE28863_A3Up0.2138869013
GSE28863_A4Up0.1691905360
GSE48662Up0.5194793210

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.