HCSGD entry for ITGB8
1. General information
| Official gene symbol | ITGB8 |
|---|---|
| Entrez ID | 3696 |
| Gene full name | integrin, beta 8 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001573 | Ganglioside metabolic process | IEA | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005102 | Receptor binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007160 | Cell-matrix adhesion | IEA | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | IEA | biological_process |
| GO:0008305 | Integrin complex | IEA | cellular_component |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0060674 | Placenta blood vessel development | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0159749174 | 0.0948344060 | 0.3124499257 | 0.5871880499 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8605529131 |
| GSE13712_SHEAR | Down | -0.0310046842 |
| GSE13712_STATIC | Up | 0.5791133871 |
| GSE19018 | Down | -0.3429275561 |
| GSE19899_A1 | Up | 0.2142158475 |
| GSE19899_A2 | Down | -0.0615038808 |
| PubMed_21979375_A1 | Up | 1.0627887484 |
| PubMed_21979375_A2 | Up | 0.4584050624 |
| GSE35957 | Up | 1.3060948331 |
| GSE36640 | Down | -0.8274870597 |
| GSE54402 | Down | -1.3450073415 |
| GSE9593 | Up | 0.1178003503 |
| GSE43922 | Up | 0.6933160580 |
| GSE24585 | Down | -0.4834121258 |
| GSE37065 | Up | 0.4260320826 |
| GSE28863_A1 | Up | 0.6440444552 |
| GSE28863_A2 | Up | 2.1766609073 |
| GSE28863_A3 | Up | 0.0694358363 |
| GSE28863_A4 | Down | -0.3554869514 |
| GSE48662 | Up | 0.2524111274 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT006494 | Immunofluorescence//Luciferase reporter assay//qRT-PCR//GFP reporter assay//In situ hybridization//Microarray//Western blot | Functional MTI | 21701675 |
| hsa-miR-19b-1-5p | MIMAT0004491 | MIRT006279 | Luciferase reporter assay | Non-Functional MTI | 22197821 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT004104 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20956944 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT019022 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
