HCSGD entry for ITGB8


1. General information

Official gene symbolITGB8
Entrez ID3696
Gene full nameintegrin, beta 8
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001573Ganglioside metabolic processIEAbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0005102Receptor bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0007155Cell adhesionTASbiological_process
GO:0007160Cell-matrix adhesionIEAbiological_process
GO:0007229Integrin-mediated signaling pathwayIEAbiological_process
GO:0008305Integrin complexIEAcellular_component
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0060674Placenta blood vessel developmentTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01597491740.09483440600.31244992570.5871880499

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.8605529131
GSE13712_SHEARDown-0.0310046842
GSE13712_STATICUp0.5791133871
GSE19018Down-0.3429275561
GSE19899_A1Up0.2142158475
GSE19899_A2Down-0.0615038808
PubMed_21979375_A1Up1.0627887484
PubMed_21979375_A2Up0.4584050624
GSE35957Up1.3060948331
GSE36640Down-0.8274870597
GSE54402Down-1.3450073415
GSE9593Up0.1178003503
GSE43922Up0.6933160580
GSE24585Down-0.4834121258
GSE37065Up0.4260320826
GSE28863_A1Up0.6440444552
GSE28863_A2Up2.1766609073
GSE28863_A3Up0.0694358363
GSE28863_A4Down-0.3554869514
GSE48662Up0.2524111274

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT006494Immunofluorescence//Luciferase reporter assay//qRT-PCR//GFP reporter assay//In situ hybridization//Microarray//Western blotFunctional MTI21701675
hsa-miR-19b-1-5pMIMAT0004491MIRT006279Luciferase reporter assayNon-Functional MTI22197821
hsa-miR-93-5pMIMAT0000093MIRT004104Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI20956944
hsa-miR-335-5pMIMAT0000765MIRT019022MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.