HCSGD entry for EIF6
1. General information
| Official gene symbol | EIF6 |
|---|---|
| Entrez ID | 3692 |
| Gene full name | eukaryotic translation initiation factor 6 |
| Other gene symbols | CAB EIF3A ITGB4BP b(2)gcn eIF-6 p27(BBP) p27BBP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003743 | Translation initiation factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005638 | Lamin filament | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0042256 | Mature ribosome assembly | IEA IMP | biological_process |
| GO:0043022 | Ribosome binding | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1097876714 | 0.8316042096 | 0.6869827906 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4012217252 |
| GSE13712_SHEAR | Up | 0.4634759184 |
| GSE13712_STATIC | Up | 0.4950930730 |
| GSE19018 | Up | 0.1893692706 |
| GSE19899_A1 | Up | 0.3272403518 |
| GSE19899_A2 | Up | 0.2354199747 |
| PubMed_21979375_A1 | Up | 0.7779100615 |
| PubMed_21979375_A2 | Up | 0.0148954020 |
| GSE35957 | Down | -0.3397700811 |
| GSE36640 | Down | -0.1904634584 |
| GSE54402 | Up | 0.2428939031 |
| GSE9593 | Up | 0.1101650047 |
| GSE43922 | Down | -0.0139807200 |
| GSE24585 | Down | -0.3790419558 |
| GSE37065 | Down | -0.1071303166 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0503965740 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042302 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049555 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
