HCSGD entry for EIF6


1. General information

Official gene symbolEIF6
Entrez ID3692
Gene full nameeukaryotic translation initiation factor 6
Other gene symbolsCAB EIF3A ITGB4BP b(2)gcn eIF-6 p27(BBP) p27BBP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003743Translation initiation factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005638Lamin filamentIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0042256Mature ribosome assemblyIEA IMPbiological_process
GO:0043022Ribosome bindingIDA IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10978767140.83160420960.68698279061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4012217252
GSE13712_SHEARUp0.4634759184
GSE13712_STATICUp0.4950930730
GSE19018Up0.1893692706
GSE19899_A1Up0.3272403518
GSE19899_A2Up0.2354199747
PubMed_21979375_A1Up0.7779100615
PubMed_21979375_A2Up0.0148954020
GSE35957Down-0.3397700811
GSE36640Down-0.1904634584
GSE54402Up0.2428939031
GSE9593Up0.1101650047
GSE43922Down-0.0139807200
GSE24585Down-0.3790419558
GSE37065Down-0.1071303166
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0503965740

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042302CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049555CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.