HCSGD entry for PDX1

1. General information

Official gene symbolPDX1
Entrez ID3651
Gene full namepancreatic and duodenal homeobox 1
Other gene symbolsGSF IDX-1 IPF1 IUF1 MODY4 PDX-1 STF-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001046Core promoter sequence-specific DNA bindingIEAmolecular_function
GO:0001889Liver developmentIEAbiological_process
GO:0003309Type B pancreatic cell differentiationIDA ISSbiological_process
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0006006Glucose metabolic processIEAbiological_process
GO:0006091Generation of precursor metabolites and energyTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0007224Smoothened signaling pathwayIEAbiological_process
GO:0007263Nitric oxide mediated signal transductionIDAbiological_process
GO:0007417Central nervous system developmentIEAbiological_process
GO:0008134Transcription factor bindingIEAmolecular_function
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0009611Response to woundingIEAbiological_process
GO:0009887Organ morphogenesisTASbiological_process
GO:0010040Response to iron(II) ionIEAbiological_process
GO:0010157Response to chlorateIEAbiological_process
GO:0010260Organ senescenceIEAbiological_process
GO:0010942Positive regulation of cell deathIEAbiological_process
GO:0016331Morphogenesis of embryonic epitheliumIEAbiological_process
GO:0030073Insulin secretionIDAbiological_process
GO:0031017Exocrine pancreas developmentIEAbiological_process
GO:0031018Endocrine pancreas developmentTASbiological_process
GO:0031100Organ regenerationIEAbiological_process
GO:0032024Positive regulation of insulin secretionIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0033273Response to vitaminIEAbiological_process
GO:0034097Response to cytokineIEAbiological_process
GO:0035094Response to nicotineIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042593Glucose homeostasisIEAbiological_process
GO:0043201Response to leucineIEAbiological_process
GO:0043388Positive regulation of DNA bindingIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048565Digestive tract developmentIEAbiological_process
GO:0048863Stem cell differentiationIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051594Detection of glucoseISSbiological_process
GO:0060290TransdifferentiationIEAbiological_process
GO:0070542Response to fatty acidIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64716277500.86587305950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0308912542
GSE13712_SHEARDown-0.0545223430
GSE13712_STATICDown-0.0340448624
GSE19018Up0.0556644667
GSE19899_A1Up0.0567725424
GSE19899_A2Up0.0333311325
PubMed_21979375_A1Down-0.0318673568
PubMed_21979375_A2Down-0.2647431213
GSE35957Up0.2811919399
GSE36640Up0.0160641728
GSE54402Up0.0436945274
GSE9593Up0.0003841618
GSE43922Up0.2379500317
GSE24585Up0.0560963750
GSE37065Up0.0465824689
GSE28863_A1Down-0.0377341626
GSE28863_A2Down-0.0892679493
GSE28863_A3Up0.1850268500
GSE28863_A4Up0.1022347138
GSE48662Down-0.0105654023

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.