HCSGD entry for INPP5B

1. General information

Official gene symbolINPP5B
Entrez ID3633
Gene full nameinositol polyphosphate-5-phosphatase, 75kDa
Other gene symbols5PTase
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0004439Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005793Endoplasmic reticulum-Golgi intermediate compartmentIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030317Sperm motilityIEAbiological_process
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0031901Early endosome membraneIEAcellular_component
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046856Phosphatidylinositol dephosphorylationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0052658Inositol-1,4,5-trisphosphate 5-phosphatase activityIDAmolecular_function
GO:0070613Regulation of protein processingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93001779950.10604318220.99999024730.6235033936

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0846064524
GSE13712_SHEARDown-0.0478279516
GSE13712_STATICDown-0.0370544137
GSE19018Up0.1381933340
GSE19899_A1Down-0.0761932890
GSE19899_A2Down-0.5368210149
PubMed_21979375_A1Down-0.4522658997
PubMed_21979375_A2Down-0.5964169199
GSE35957Down-0.2597267805
GSE36640Down-0.0182340164
GSE54402Down-0.1381186639
GSE9593Down-0.1430666656
GSE43922Down-0.6696257522
GSE24585Up0.5660781404
GSE37065Down-0.0465827695
GSE28863_A1Up0.0681996059
GSE28863_A2Down-0.1734507722
GSE28863_A3Up0.1280767145
GSE28863_A4Down-0.0280346367
GSE48662Down-0.0313461116

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

D-Myo-Inositol-1,4-BisphosphateDB03158 EXPT00125

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030250MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.