HCSGD entry for INPP5B

1. General information

Official gene symbolINPP5B
Entrez ID3633
Gene full nameinositol polyphosphate-5-phosphatase, 75kDa
Other gene symbols5PTase
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0004439Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005793Endoplasmic reticulum-Golgi intermediate compartmentIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030317Sperm motilityIEAbiological_process
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0031901Early endosome membraneIEAcellular_component
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046856Phosphatidylinositol dephosphorylationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0052658Inositol-1,4,5-trisphosphate 5-phosphatase activityIDAmolecular_function
GO:0070613Regulation of protein processingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93001779950.10604318220.99999024730.6235033936

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0846064524
GSE13712_SHEARDown-0.0478279516
GSE13712_STATICDown-0.0370544137
GSE19018Up0.1381933340
GSE19899_A1Down-0.0761932890
GSE19899_A2Down-0.5368210149
PubMed_21979375_A1Down-0.4522658997
PubMed_21979375_A2Down-0.5964169199
GSE35957Down-0.2597267805
GSE36640Down-0.0182340164
GSE54402Down-0.1381186639
GSE9593Down-0.1430666656
GSE43922Down-0.6696257522
GSE24585Up0.5660781404
GSE37065Down-0.0465827695
GSE28863_A1Up0.0681996059
GSE28863_A2Down-0.1734507722
GSE28863_A3Up0.1280767145
GSE28863_A4Down-0.0280346367
GSE48662Down-0.0313461116

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

D-Myo-Inositol-1,4-BisphosphateDB03158 EXPT00125

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030250MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.