HCSGD entry for IMPA1
1. General information
| Official gene symbol | IMPA1 |
|---|---|
| Entrez ID | 3612 |
| Gene full name | inositol(myo)-1(or 4)-monophosphatase 1 |
| Other gene symbols | IMP IMPA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006021 | Inositol biosynthetic process | IEA | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | IMP | biological_process |
| GO:0006796 | Phosphate-containing compound metabolic process | IMP | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0008934 | Inositol monophosphate 1-phosphatase activity | IDA IMP | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046854 | Phosphatidylinositol phosphorylation | IEA | biological_process |
| GO:0046855 | Inositol phosphate dephosphorylation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0052832 | Inositol monophosphate 3-phosphatase activity | IEA | molecular_function |
| GO:0052833 | Inositol monophosphate 4-phosphatase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1587745184 | 0.1650245659 | 0.7901501418 | 0.7861740452 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0798484954 |
| GSE13712_SHEAR | Up | 0.0267528457 |
| GSE13712_STATIC | Up | 0.2295247217 |
| GSE19018 | Down | -0.4391802846 |
| GSE19899_A1 | Up | 0.1117671800 |
| GSE19899_A2 | Up | 0.1879970144 |
| PubMed_21979375_A1 | Up | 1.0202991876 |
| PubMed_21979375_A2 | Up | 0.0306717284 |
| GSE35957 | Down | -0.0859011664 |
| GSE36640 | Down | -0.0769592920 |
| GSE54402 | Up | 0.2926571732 |
| GSE9593 | Down | -0.1570920047 |
| GSE43922 | Up | 0.0614785704 |
| GSE24585 | Up | 0.2250552228 |
| GSE37065 | Up | 0.3186815158 |
| GSE28863_A1 | Up | 0.7280707008 |
| GSE28863_A2 | Down | -1.3548247690 |
| GSE28863_A3 | Down | -0.2952534338 |
| GSE28863_A4 | Down | -0.3387103256 |
| GSE48662 | Down | -0.2763228992 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT006254 | Luciferase reporter assay | Functional MTI | 22301190 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021823 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024884 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026629 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-365a-3p | MIMAT0000710 | MIRT044020 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT050020 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
