HCSGD entry for IMPA1


1. General information

Official gene symbolIMPA1
Entrez ID3612
Gene full nameinositol(myo)-1(or 4)-monophosphatase 1
Other gene symbolsIMP IMPA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006021Inositol biosynthetic processIEAbiological_process
GO:0006661Phosphatidylinositol biosynthetic processIMPbiological_process
GO:0006796Phosphate-containing compound metabolic processIMPbiological_process
GO:0007165Signal transductionIMPbiological_process
GO:0008934Inositol monophosphate 1-phosphatase activityIDA IMPmolecular_function
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046854Phosphatidylinositol phosphorylationIEAbiological_process
GO:0046855Inositol phosphate dephosphorylationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0052832Inositol monophosphate 3-phosphatase activityIEAmolecular_function
GO:0052833Inositol monophosphate 4-phosphatase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15877451840.16502456590.79015014180.7861740452

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0798484954
GSE13712_SHEARUp0.0267528457
GSE13712_STATICUp0.2295247217
GSE19018Down-0.4391802846
GSE19899_A1Up0.1117671800
GSE19899_A2Up0.1879970144
PubMed_21979375_A1Up1.0202991876
PubMed_21979375_A2Up0.0306717284
GSE35957Down-0.0859011664
GSE36640Down-0.0769592920
GSE54402Up0.2926571732
GSE9593Down-0.1570920047
GSE43922Up0.0614785704
GSE24585Up0.2250552228
GSE37065Up0.3186815158
GSE28863_A1Up0.7280707008
GSE28863_A2Down-1.3548247690
GSE28863_A3Down-0.2952534338
GSE28863_A4Down-0.3387103256
GSE48662Down-0.2763228992

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LithiumDB01356 -
L-Myo-Inositol-1-PhosphateDB03542 EXPT02036

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT006254Luciferase reporter assayFunctional MTI22301190
hsa-miR-132-3pMIMAT0000426MIRT021823MicroarrayFunctional MTI (Weak)17612493
hsa-miR-215-5pMIMAT0000272MIRT024884MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026629MicroarrayFunctional MTI (Weak)19074876
hsa-miR-365a-3pMIMAT0000710MIRT044020CLASHFunctional MTI (Weak)23622248
hsa-miR-27a-3pMIMAT0000084MIRT050020CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.