HCSGD entry for ACADM

1. General information

Official gene symbolACADM
Entrez ID34
Gene full nameacyl-CoA dehydrogenase, C-4 to C-12 straight chain
Other gene symbolsACAD1 MCAD MCADH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001889Liver developmentIEAbiological_process
GO:0003995Acyl-CoA dehydrogenase activityIDA IEA IMP TASmolecular_function
GO:0005739MitochondrionIDA IEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005978Glycogen biosynthetic processIEAbiological_process
GO:0006111Regulation of gluconeogenesisIEAbiological_process
GO:0006635Fatty acid beta-oxidationIMP TASbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016627Oxidoreductase activity, acting on the CH-CH group of donorsIEAmolecular_function
GO:0019254Carnitine metabolic process, CoA-linkedIEA IMPbiological_process
GO:0030424AxonIDAcellular_component
GO:0033539Fatty acid beta-oxidation using acyl-CoA dehydrogenaseIDA IEA IMPbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0042802Identical protein bindingIDAmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045329Carnitine biosynthetic processIMPbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
GO:0051791Medium-chain fatty acid metabolic processIDA IEAbiological_process
GO:0051793Medium-chain fatty acid catabolic processIDAbiological_process
GO:0055007Cardiac muscle cell differentiationIEAbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0070991Medium-chain-acyl-CoA dehydrogenase activityIDA IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96065831470.01812453170.99999024730.2633632450

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2035891361
GSE13712_SHEARDown-0.1603415423
GSE13712_STATICDown-0.2662115801
GSE19018Down-0.4122767368
GSE19899_A1Down-0.3002803307
GSE19899_A2Down-0.2321672532
PubMed_21979375_A1Up0.2043080714
PubMed_21979375_A2Down-0.9233284190
GSE35957Down-0.0013663198
GSE36640Down-0.5611906459
GSE54402Up0.1944465370
GSE9593Down-0.8091213136
GSE43922Down-0.4456355295
GSE24585Up0.5460795733
GSE37065Up0.0005096999
GSE28863_A1Down-0.4335373663
GSE28863_A2Down-0.3243872571
GSE28863_A3Up0.1046729353
GSE28863_A4Up0.0361747893
GSE48662Down-0.3613392112

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Octanoyl-Coenzyme ADB02910 EXPT00977
3-Thiaoctanoyl-Coenzyme ADB03415 EXPT01029

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT004953qRT-PCRFunctional MTI (Weak)17942906
hsa-miR-128-3pMIMAT0000424MIRT021871MicroarrayFunctional MTI (Weak)17612493
hsa-miR-26b-5pMIMAT0000083MIRT028946MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.