HCSGD entry for ACADM

1. General information

Official gene symbolACADM
Entrez ID34
Gene full nameacyl-CoA dehydrogenase, C-4 to C-12 straight chain
Other gene symbolsACAD1 MCAD MCADH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001889Liver developmentIEAbiological_process
GO:0003995Acyl-CoA dehydrogenase activityIDA IEA IMP TASmolecular_function
GO:0005739MitochondrionIDA IEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005978Glycogen biosynthetic processIEAbiological_process
GO:0006111Regulation of gluconeogenesisIEAbiological_process
GO:0006635Fatty acid beta-oxidationIMP TASbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016627Oxidoreductase activity, acting on the CH-CH group of donorsIEAmolecular_function
GO:0019254Carnitine metabolic process, CoA-linkedIEA IMPbiological_process
GO:0030424AxonIDAcellular_component
GO:0033539Fatty acid beta-oxidation using acyl-CoA dehydrogenaseIDA IEA IMPbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0042802Identical protein bindingIDAmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045329Carnitine biosynthetic processIMPbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
GO:0051791Medium-chain fatty acid metabolic processIDA IEAbiological_process
GO:0051793Medium-chain fatty acid catabolic processIDAbiological_process
GO:0055007Cardiac muscle cell differentiationIEAbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0070991Medium-chain-acyl-CoA dehydrogenase activityIDA IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96065831470.01812453170.99999024730.2633632450

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2035891361
GSE13712_SHEARDown-0.1603415423
GSE13712_STATICDown-0.2662115801
GSE19018Down-0.4122767368
GSE19899_A1Down-0.3002803307
GSE19899_A2Down-0.2321672532
PubMed_21979375_A1Up0.2043080714
PubMed_21979375_A2Down-0.9233284190
GSE35957Down-0.0013663198
GSE36640Down-0.5611906459
GSE54402Up0.1944465370
GSE9593Down-0.8091213136
GSE43922Down-0.4456355295
GSE24585Up0.5460795733
GSE37065Up0.0005096999
GSE28863_A1Down-0.4335373663
GSE28863_A2Down-0.3243872571
GSE28863_A3Up0.1046729353
GSE28863_A4Up0.0361747893
GSE48662Down-0.3613392112

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Octanoyl-Coenzyme ADB02910 EXPT00977
3-Thiaoctanoyl-Coenzyme ADB03415 EXPT01029

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT004953qRT-PCRFunctional MTI (Weak)17942906
hsa-miR-128-3pMIMAT0000424MIRT021871MicroarrayFunctional MTI (Weak)17612493
hsa-miR-26b-5pMIMAT0000083MIRT028946MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.