HCSGD entry for APOA4

1. General information

Official gene symbolAPOA4
Entrez ID337
Gene full nameapolipoprotein A-IV
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0002227Innate immune response in mucosaIDAbiological_process
GO:0005319Lipid transporter activityTASmolecular_function
GO:0005507Copper ion bindingIDAmolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005769Early endosomeTAScellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006869Lipid transportIDAbiological_process
GO:0006982Response to lipid hydroperoxideIDAbiological_process
GO:0007159Leukocyte cell-cell adhesionIDAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008203Cholesterol metabolic processIDAbiological_process
GO:0008289Lipid bindingIMPmolecular_function
GO:0009986Cell surfaceIDAcellular_component
GO:0010873Positive regulation of cholesterol esterificationIDAbiological_process
GO:0010898Positive regulation of triglyceride catabolic processIDAbiological_process
GO:0016209Antioxidant activityIDAmolecular_function
GO:0017127Cholesterol transporter activityIDAmolecular_function
GO:0019430Removal of superoxide radicalsIDAbiological_process
GO:0030300Regulation of intestinal cholesterol absorptionIEAbiological_process
GO:0031210Phosphatidylcholine bindingIDAmolecular_function
GO:0032374Regulation of cholesterol transportIDAbiological_process
GO:0033344Cholesterol effluxIDAbiological_process
GO:0033700Phospholipid effluxIDAbiological_process
GO:0034361Very-low-density lipoprotein particleIDAcellular_component
GO:0034364High-density lipoprotein particleIDAcellular_component
GO:0034371Chylomicron remodelingICbiological_process
GO:0034372Very-low-density lipoprotein particle remodelingIDAbiological_process
GO:0034375High-density lipoprotein particle remodelingICbiological_process
GO:0034378Chylomicron assemblyTASbiological_process
GO:0034445Negative regulation of plasma lipoprotein particle oxidationIDAbiological_process
GO:0035634Response to stilbenoidIEAbiological_process
GO:0042157Lipoprotein metabolic processTASbiological_process
GO:0042627ChylomicronIDAcellular_component
GO:0042632Cholesterol homeostasisIDAbiological_process
GO:0042744Hydrogen peroxide catabolic processIDAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043691Reverse cholesterol transportIDAbiological_process
GO:0044240Multicellular organismal lipid catabolic processIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045723Positive regulation of fatty acid biosynthetic processIDAbiological_process
GO:0046470Phosphatidylcholine metabolic processIDAbiological_process
GO:0051006Positive regulation of lipoprotein lipase activityIDAbiological_process
GO:0055088Lipid homeostasisIDAbiological_process
GO:0060228Phosphatidylcholine-sterol O-acyltransferase activator activityIDAmolecular_function
GO:0065005Protein-lipid complex assemblyIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66093777210.68488244750.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1049791830
GSE13712_SHEARDown-0.0228706617
GSE13712_STATICDown-0.0132634414
GSE19018Up0.0730830030
GSE19899_A1Up0.0551639228
GSE19899_A2Up0.3886046818
PubMed_21979375_A1Down-0.2030121868
PubMed_21979375_A2Down-0.2390415909
GSE35957Up0.0642504459
GSE36640Up0.2612057518
GSE54402Up0.0202573348
GSE9593Up0.0771889548
GSE43922Up0.1442134806
GSE24585Down-0.0278403600
GSE37065Down-0.0684201446
GSE28863_A1Down-0.1600475098
GSE28863_A2Up0.0025881844
GSE28863_A3Up0.1316951660
GSE28863_A4Down-0.0225833102
GSE48662Up0.0293218205

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.