HCSGD entry for APOA4

1. General information

Official gene symbolAPOA4
Entrez ID337
Gene full nameapolipoprotein A-IV
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0002227Innate immune response in mucosaIDAbiological_process
GO:0005319Lipid transporter activityTASmolecular_function
GO:0005507Copper ion bindingIDAmolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005769Early endosomeTAScellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006869Lipid transportIDAbiological_process
GO:0006982Response to lipid hydroperoxideIDAbiological_process
GO:0007159Leukocyte cell-cell adhesionIDAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008203Cholesterol metabolic processIDAbiological_process
GO:0008289Lipid bindingIMPmolecular_function
GO:0009986Cell surfaceIDAcellular_component
GO:0010873Positive regulation of cholesterol esterificationIDAbiological_process
GO:0010898Positive regulation of triglyceride catabolic processIDAbiological_process
GO:0016209Antioxidant activityIDAmolecular_function
GO:0017127Cholesterol transporter activityIDAmolecular_function
GO:0019430Removal of superoxide radicalsIDAbiological_process
GO:0030300Regulation of intestinal cholesterol absorptionIEAbiological_process
GO:0031210Phosphatidylcholine bindingIDAmolecular_function
GO:0032374Regulation of cholesterol transportIDAbiological_process
GO:0033344Cholesterol effluxIDAbiological_process
GO:0033700Phospholipid effluxIDAbiological_process
GO:0034361Very-low-density lipoprotein particleIDAcellular_component
GO:0034364High-density lipoprotein particleIDAcellular_component
GO:0034371Chylomicron remodelingICbiological_process
GO:0034372Very-low-density lipoprotein particle remodelingIDAbiological_process
GO:0034375High-density lipoprotein particle remodelingICbiological_process
GO:0034378Chylomicron assemblyTASbiological_process
GO:0034445Negative regulation of plasma lipoprotein particle oxidationIDAbiological_process
GO:0035634Response to stilbenoidIEAbiological_process
GO:0042157Lipoprotein metabolic processTASbiological_process
GO:0042627ChylomicronIDAcellular_component
GO:0042632Cholesterol homeostasisIDAbiological_process
GO:0042744Hydrogen peroxide catabolic processIDAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043691Reverse cholesterol transportIDAbiological_process
GO:0044240Multicellular organismal lipid catabolic processIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045723Positive regulation of fatty acid biosynthetic processIDAbiological_process
GO:0046470Phosphatidylcholine metabolic processIDAbiological_process
GO:0051006Positive regulation of lipoprotein lipase activityIDAbiological_process
GO:0055088Lipid homeostasisIDAbiological_process
GO:0060228Phosphatidylcholine-sterol O-acyltransferase activator activityIDAmolecular_function
GO:0065005Protein-lipid complex assemblyIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66093777210.68488244750.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1049791830
GSE13712_SHEARDown-0.0228706617
GSE13712_STATICDown-0.0132634414
GSE19018Up0.0730830030
GSE19899_A1Up0.0551639228
GSE19899_A2Up0.3886046818
PubMed_21979375_A1Down-0.2030121868
PubMed_21979375_A2Down-0.2390415909
GSE35957Up0.0642504459
GSE36640Up0.2612057518
GSE54402Up0.0202573348
GSE9593Up0.0771889548
GSE43922Up0.1442134806
GSE24585Down-0.0278403600
GSE37065Down-0.0684201446
GSE28863_A1Down-0.1600475098
GSE28863_A2Up0.0025881844
GSE28863_A3Up0.1316951660
GSE28863_A4Down-0.0225833102
GSE48662Up0.0293218205

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.