HCSGD entry for HTR1E

1. General information

Official gene symbolHTR1E
Entrez ID3354
Gene full name5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
Other gene symbols5-HT1E
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0004993Serotonin receptor activityIDA IMPmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIMPcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIMPbiological_process
GO:0007210Serotonin receptor signaling pathwayIDA IMPbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0030815Negative regulation of cAMP metabolic processIEAbiological_process
GO:0051378Serotonin bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62407207170.85859712400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1111237742
GSE13712_SHEARUp0.0551419693
GSE13712_STATICUp0.1659258007
GSE19018Up0.1139107524
GSE19899_A1Up0.0726983938
GSE19899_A2Up0.0933733164
PubMed_21979375_A1Down-0.0596229033
PubMed_21979375_A2Down-0.0461982113
GSE35957Up0.1163689587
GSE36640Up0.0174592709
GSE54402Down-0.0519475212
GSE9593Down-0.1297487927
GSE43922Up0.0165046105
GSE24585Up0.0769327946
GSE37065Down-0.0253124539
GSE28863_A1Up0.0319451430
GSE28863_A2Up0.0932197804
GSE28863_A3Up0.2190603728
GSE28863_A4Up0.0422051014
GSE48662Up0.0803144751

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

EletriptanDB00216 APRD00945
ZiprasidoneDB00246 APRD00540
OlanzapineDB00334 APRD00138
ClozapineDB00363 APRD00470
LoxapineDB00408 APRD00574
QuetiapineDB01224 APRD00675
AripiprazoleDB01238 APRD00638
KetamineDB01221 APRD00493

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.