HCSGD entry for HTR1E

1. General information

Official gene symbolHTR1E
Entrez ID3354
Gene full name5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
Other gene symbols5-HT1E
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0004993Serotonin receptor activityIDA IMPmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIMPcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIMPbiological_process
GO:0007210Serotonin receptor signaling pathwayIDA IMPbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0030815Negative regulation of cAMP metabolic processIEAbiological_process
GO:0051378Serotonin bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62407207170.85859712400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1111237742
GSE13712_SHEARUp0.0551419693
GSE13712_STATICUp0.1659258007
GSE19018Up0.1139107524
GSE19899_A1Up0.0726983938
GSE19899_A2Up0.0933733164
PubMed_21979375_A1Down-0.0596229033
PubMed_21979375_A2Down-0.0461982113
GSE35957Up0.1163689587
GSE36640Up0.0174592709
GSE54402Down-0.0519475212
GSE9593Down-0.1297487927
GSE43922Up0.0165046105
GSE24585Up0.0769327946
GSE37065Down-0.0253124539
GSE28863_A1Up0.0319451430
GSE28863_A2Up0.0932197804
GSE28863_A3Up0.2190603728
GSE28863_A4Up0.0422051014
GSE48662Up0.0803144751

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

EletriptanDB00216 APRD00945
ZiprasidoneDB00246 APRD00540
OlanzapineDB00334 APRD00138
ClozapineDB00363 APRD00470
LoxapineDB00408 APRD00574
QuetiapineDB01224 APRD00675
AripiprazoleDB01238 APRD00638
KetamineDB01221 APRD00493

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.