HCSGD entry for HOXB3

1. General information

Official gene symbolHOXB3
Entrez ID3213
Gene full namehomeobox B3
Other gene symbolsHOX2 HOX2G Hox-2.7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIEAmolecular_function
GO:0001525AngiogenesisIEPbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0021546Rhombomere developmentIEAbiological_process
GO:0021615Glossopharyngeal nerve morphogenesisIEAbiological_process
GO:0030878Thyroid gland developmentIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0050767Regulation of neurogenesisIEAbiological_process
GO:0051216Cartilage developmentIEAbiological_process
GO:0060216Definitive hemopoiesisIEAbiological_process
GO:0060324Face developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49053543940.01442490030.99999024730.2358247205

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0571195938
GSE13712_SHEARUp0.1534831915
GSE13712_STATICDown-0.0922534528
GSE19018Up0.2357739869
GSE19899_A1Down-0.7225532545
GSE19899_A2Down-0.4314764212
PubMed_21979375_A1Down-2.0519318275
PubMed_21979375_A2Down-0.9485386910
GSE35957Down-1.0160371269
GSE36640Down-0.2450709673
GSE54402Down-0.8465305948
GSE9593Down-0.3232312910
GSE43922Down-0.8409631631
GSE24585Up1.8034887846
GSE37065Down-0.0875848619
GSE28863_A1Up0.0240001842
GSE28863_A2Up0.1729393148
GSE28863_A3Up0.2300896769
GSE28863_A4Up0.2160560239
GSE48662Down-0.2578183568

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-10a-5pMIMAT0000253MIRT025627SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.