HCSGD entry for HOXB3

1. General information

Official gene symbolHOXB3
Entrez ID3213
Gene full namehomeobox B3
Other gene symbolsHOX2 HOX2G Hox-2.7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIEAmolecular_function
GO:0001525AngiogenesisIEPbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0021546Rhombomere developmentIEAbiological_process
GO:0021615Glossopharyngeal nerve morphogenesisIEAbiological_process
GO:0030878Thyroid gland developmentIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0050767Regulation of neurogenesisIEAbiological_process
GO:0051216Cartilage developmentIEAbiological_process
GO:0060216Definitive hemopoiesisIEAbiological_process
GO:0060324Face developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49053543940.01442490030.99999024730.2358247205

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0571195938
GSE13712_SHEARUp0.1534831915
GSE13712_STATICDown-0.0922534528
GSE19018Up0.2357739869
GSE19899_A1Down-0.7225532545
GSE19899_A2Down-0.4314764212
PubMed_21979375_A1Down-2.0519318275
PubMed_21979375_A2Down-0.9485386910
GSE35957Down-1.0160371269
GSE36640Down-0.2450709673
GSE54402Down-0.8465305948
GSE9593Down-0.3232312910
GSE43922Down-0.8409631631
GSE24585Up1.8034887846
GSE37065Down-0.0875848619
GSE28863_A1Up0.0240001842
GSE28863_A2Up0.1729393148
GSE28863_A3Up0.2300896769
GSE28863_A4Up0.2160560239
GSE48662Down-0.2578183568

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-10a-5pMIMAT0000253MIRT025627SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.