HCSGD entry for HMOX2

1. General information

Official gene symbolHMOX2
Entrez ID3163
Gene full nameheme oxygenase (decycling) 2
Other gene symbolsHO-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIDAbiological_process
GO:0004392Heme oxygenase (decyclizing) activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006778Porphyrin-containing compound metabolic processTASbiological_process
GO:0006788Heme oxidationIEAbiological_process
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0006979Response to oxidative stressIEAbiological_process
GO:0042167Heme catabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06589260670.69734240720.55340118061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3973623719
GSE13712_SHEARUp0.2186081137
GSE13712_STATICUp0.2093604351
GSE19018Down-0.1426483725
GSE19899_A1Up0.5284922307
GSE19899_A2Up0.8856441699
PubMed_21979375_A1Up1.0464477390
PubMed_21979375_A2Up0.3865978450
GSE35957Down-0.2364907237
GSE36640Up0.3524537818
GSE54402Up0.2738864738
GSE9593Up0.0168054683
GSE43922Up0.2434602989
GSE24585Down-0.3241588653
GSE37065Down-0.2583417431
GSE28863_A1Down-0.0633831963
GSE28863_A2Down-0.1972010156
GSE28863_A3Down-0.4907061131
GSE28863_A4Down-0.0280954937
GSE48662Down-0.0963343526

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
StannsoporfinDB04912 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT045117CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.