HCSGD entry for HMOX2

1. General information

Official gene symbolHMOX2
Entrez ID3163
Gene full nameheme oxygenase (decycling) 2
Other gene symbolsHO-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIDAbiological_process
GO:0004392Heme oxygenase (decyclizing) activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006778Porphyrin-containing compound metabolic processTASbiological_process
GO:0006788Heme oxidationIEAbiological_process
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0006979Response to oxidative stressIEAbiological_process
GO:0042167Heme catabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06589260670.69734240720.55340118061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3973623719
GSE13712_SHEARUp0.2186081137
GSE13712_STATICUp0.2093604351
GSE19018Down-0.1426483725
GSE19899_A1Up0.5284922307
GSE19899_A2Up0.8856441699
PubMed_21979375_A1Up1.0464477390
PubMed_21979375_A2Up0.3865978450
GSE35957Down-0.2364907237
GSE36640Up0.3524537818
GSE54402Up0.2738864738
GSE9593Up0.0168054683
GSE43922Up0.2434602989
GSE24585Down-0.3241588653
GSE37065Down-0.2583417431
GSE28863_A1Down-0.0633831963
GSE28863_A2Down-0.1972010156
GSE28863_A3Down-0.4907061131
GSE28863_A4Down-0.0280954937
GSE48662Down-0.0963343526

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
StannsoporfinDB04912 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT045117CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.