HCSGD entry for HLA-F

1. General information

Official gene symbolHLA-F
Entrez ID3134
Gene full namemajor histocompatibility complex, class I, F
Other gene symbolsCDA12 HLA-5.4 HLA-CDA12 HLAF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001916Positive regulation of T cell mediated cytotoxicityIEAbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class IIEA TASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0002480Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentTASbiological_process
GO:0005102Receptor bindingIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseIEAbiological_process
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030670Phagocytic vesicle membraneTAScellular_component
GO:0031901Early endosome membraneTAScellular_component
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042605Peptide antigen bindingIBA IEAmolecular_function
GO:0042612MHC class I protein complexIEAcellular_component
GO:0050776Regulation of immune responseTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33361275410.41908551350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1602810098
GSE13712_SHEARUp0.5967678449
GSE13712_STATICUp0.5845434779
GSE19018Up0.6971670845
GSE19899_A1Down-0.1641005842
GSE19899_A2Up0.2144927752
PubMed_21979375_A1Down-0.1749823132
PubMed_21979375_A2Down-0.5958502179
GSE35957Down-0.5923868852
GSE36640Up0.7327798026
GSE54402Down-0.0620656645
GSE9593Down-0.1132904186
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.1370665078
GSE28863_A2Up0.2175013013
GSE28863_A3Up0.0140606248
GSE28863_A4Down-0.0706363128
GSE48662Down-0.2402632161

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.