HCSGD entry for HLA-F

1. General information

Official gene symbolHLA-F
Entrez ID3134
Gene full namemajor histocompatibility complex, class I, F
Other gene symbolsCDA12 HLA-5.4 HLA-CDA12 HLAF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001916Positive regulation of T cell mediated cytotoxicityIEAbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class IIEA TASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0002480Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentTASbiological_process
GO:0005102Receptor bindingIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseIEAbiological_process
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030670Phagocytic vesicle membraneTAScellular_component
GO:0031901Early endosome membraneTAScellular_component
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042605Peptide antigen bindingIBA IEAmolecular_function
GO:0042612MHC class I protein complexIEAcellular_component
GO:0050776Regulation of immune responseTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33361275410.41908551350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1602810098
GSE13712_SHEARUp0.5967678449
GSE13712_STATICUp0.5845434779
GSE19018Up0.6971670845
GSE19899_A1Down-0.1641005842
GSE19899_A2Up0.2144927752
PubMed_21979375_A1Down-0.1749823132
PubMed_21979375_A2Down-0.5958502179
GSE35957Down-0.5923868852
GSE36640Up0.7327798026
GSE54402Down-0.0620656645
GSE9593Down-0.1132904186
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.1370665078
GSE28863_A2Up0.2175013013
GSE28863_A3Up0.0140606248
GSE28863_A4Down-0.0706363128
GSE48662Down-0.2402632161

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.