HCSGD entry for HLA-DRB4

1. General information

Official gene symbolHLA-DRB4
Entrez ID3126
Gene full namemajor histocompatibility complex, class II, DR beta 4
Other gene symbolsDR-4 DR4 DRB4 HLA-DR4B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0005765Lysosomal membraneIDA TAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030658Transport vesicle membraneTAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031295T cell costimulationTASbiological_process
GO:0031902Late endosome membraneIDAcellular_component
GO:0032588Trans-Golgi network membraneTAScellular_component
GO:0042613MHC class II protein complexIEAcellular_component
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92008087460.64933360050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1234100297
GSE13712_SHEARDown-0.1001812681
GSE13712_STATICUp0.1492970596
GSE19018Up0.0964892263
GSE19899_A1Up0.0907353318
GSE19899_A2Down-0.0392478289
PubMed_21979375_A1Up0.0286512365
PubMed_21979375_A2Down-0.0595180737
GSE35957Down-0.1496797522
GSE36640Down-0.0247675564
GSE54402Up0.0524644727
GSE9593Down-0.0770576367
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.2681420338

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.