HCSGD entry for HLA-DRB4

1. General information

Official gene symbolHLA-DRB4
Entrez ID3126
Gene full namemajor histocompatibility complex, class II, DR beta 4
Other gene symbolsDR-4 DR4 DRB4 HLA-DR4B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0005765Lysosomal membraneIDA TAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030658Transport vesicle membraneTAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031295T cell costimulationTASbiological_process
GO:0031902Late endosome membraneIDAcellular_component
GO:0032588Trans-Golgi network membraneTAScellular_component
GO:0042613MHC class II protein complexIEAcellular_component
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92008087460.64933360050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1234100297
GSE13712_SHEARDown-0.1001812681
GSE13712_STATICUp0.1492970596
GSE19018Up0.0964892263
GSE19899_A1Up0.0907353318
GSE19899_A2Down-0.0392478289
PubMed_21979375_A1Up0.0286512365
PubMed_21979375_A2Down-0.0595180737
GSE35957Down-0.1496797522
GSE36640Down-0.0247675564
GSE54402Up0.0524644727
GSE9593Down-0.0770576367
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.2681420338

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.